Search on:
EDAR-ASSOCIATED DEATH DOMAIN PROTEIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Edar-Associated Death Domain Protein
Descriptor
Spanish
:
Proteína de Dominio de Muerte Asociada a Edar
Descriptor
Portuguese
:
Proteína de Domínio de Morte Associada a Edar
Tree Number:
D12.644.360.024.296.100
D12.644.360.024.500.061
D12.644.360.075.421.100
D12.776.157.057.024.100
D12.776.157.057.500.061
D12.776.476.024.375.100
D12.776.476.024.500.061
D12.776.476.075.421.100
Definition
English
:
A tumor
necrosis
factor receptor-associated factor that acts as a specific signaling adaptor protein for the
EDAR RECEPTOR
and plays an important
role
in ectodermal development. It binds to
edar receptor
via its C-terminal
death
domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of
edar-associated death domain protein
is associated with AUTOSOMAL RECESSIVE ANHIDROTIC
ECTODERMAL DYSPLASIA.
Entry Combination - descr/qualif
English
:
Edar-Associated Death Domain Protein
/
deficiency
use
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive
History Note
English
:
2007(2002)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52310
Unique Identifier:
D053362
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS